Tuberculin response in preterm infants after BCG vaccination at birth.

Tuberculin skin reactivity after neonatal BCG vaccination in preterm infants in Minas Gerais, Brazil, 2001-2002.

OBJECTIVES The efficacy of BCG vaccination in preterm babies is unknown, and available data on conversion rates to tuberculin in this age group are scarce and controversial. This study assessed the tuberculin response in preterm infants after BCG vaccination. METHODS This randomized cohort study was carried out at the Neonatal Department, University Hospital, Federal University of Minas Gerai...

Evalution of Tuberculin Skin Test Four Months after BCG Vaccination at Birth

Tuberculin sensitivity in low birth weight and malnourished children.

In India, pediatricians compared data on 240 low birth weight (LBW) infants with data on normal birth weight infants and data on 224 malnourished children with data on children of normal nutritional status to determine the tuberculin status of the two immunocompromised groups who received BCG vaccination at birth. No child had third degree or severe malnutrition. The pediatricians used PPD in...

Timing and dose of BCG vaccination in infants as assessed by postvaccination tuberculin sensitivity.

Tuberculosis is an important public health problem in developing countries and BCG plays an important role in preventing serious form of the disease in children. BCG induced tuberculin sensitivity is a quantitative characteristic and has been used to compare vaccine efficacy. The standard dose of BCG vaccine is 0.1mg in 1 ml though manufacturers of certain strains of BCG, i.e., Copenhagen 1331 ...

Safety and eVectiveness of BCG vaccination in preterm babies

Aim—To assess the cell mediated immune response to BCG vaccine in preterm babies. Methods—Sixty two consecutive preterm babies born at < 35 weeks of gestation were randomly allocated into two groups. Babies in group A were vaccinated early at 34–35 weeks and group B were vaccinated late at 38–40 weeks of postconceptional age. The two groups were similar in terms of: gestational age (mean (SD) 3...